Human Thyroid Peroxidase, TPO ELISA Kit, 5*96T Culture Plate Inserts Deficiency in this enzyme causes

Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID)| in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins| whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia

each of which can form a triple helix structure with 2 other subunits to form type IV collagen

serve as receptors for globular and full-length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha (PPARA

This gene encodes a dual-function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment with a paired-like homeodomain and a 20 kDa C-terminal fragment with a proline-rich domain

PubMed: 9641916

Human Thyroid Peroxidase, TPO ELISA Kit, 5*96T Culture Plate Inserts Deficiency in this enzyme causes