NBK(Phospho Thr33) Polyclonal Antibody, 50ul Digital Burette ANX4 has 45 to 59%

ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization

the formation of actin stress fibers and focal adhesions

This gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins

it has been shown that this protein plays a role in membrane traffic that is independent of translation and that it is required for exocytosis from erythroleukemia cells

A related pseudogene is located on chromosome 9

NBK(Phospho Thr33) Polyclonal Antibody, 50ul Digital Burette ANX4 has 45 to 59%The protein encoded by this gene shares a critical BH3 domain with other death promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro apoptotic activity, and for interaction with anti apoptotic members of the BCL2 family, and viral survival promoting proteins. Since the activity of this protein is suppressed in the presence of survival promoting proteins, it is suggested as a likely target for anti apoptotic proteins.