P311 Polyclonal Antibody, 100ul Cellular Function Assays The CHD family of proteins

The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains

PSMB11| or beta-5t| is a catalytic subunit expressed exclusively in cortical thymic epithelial cells (Murata et al

Defects in this gene can also cause cone-rod dystrophy type 11| a disease characterized by the initial degeneration of cone photoreceptor cells and resulting in loss of color vision and visual acuity| followed by the degeneration of rod photoreceptor cells| which progresses to night blindness and the loss of peripheral vision

however its substrate specificity is currently unknown

A mutation in this gene has been correlated with T-cell immunodeficiency

P311 Polyclonal Antibody, 100ul Cellular Function Assays The CHD family of proteinsP311, also known as C5orf13 (chromosome 5 open reading frame 13), D4S114, PTZ17 or PRO1873, is a 68 amino acid cytoplasmic protein involved in cellular differentiation, neural function and axonal regeneration. Found in the granular layer of the cerebellum, P311 is expressed at lower levels in hippocampus, olfactory bulb, kidney, liver and heart and when expressed ectopically, P311 augments giloma motility. P311 is enriched in mice within the