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ATG4a Rabbit Polyclonal Antibody, 20ul Protein Post-translational Modification Loss of function of this

SKU: 16768449284

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ATG4a Rabbit Polyclonal Antibody, 20ul Protein Post-translational Modification Loss of function of thisAutophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene

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Description

Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability

This gene encodes a secreted chaperone protein that prevents the aggregation of other secreted proteins| including proteins that are associated with neurodegenerative and metabolic disease

Contains 13 laminin EGF-like domains

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver| spleen and bone marrow

It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation| DNA repair| and/or cell cycle checkpoint control

ATG4a Rabbit Polyclonal Antibody, 20ul Protein Post-translational Modification Loss of function of thisAutophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene

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