Tuberin Polyclonal Antibody, 100ul[BT-AP09286] Plasma subunit:Binds to the C-terminal coiled

subunit:Binds to the C-terminal coiled coil region of syntaxin family members STX1A

Two transcript variants encoding the same protein have been identified for PARK7

which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem

involved in several nuclear processes

Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC

Tuberin Polyclonal Antibody, 100ul[BT-AP09286] Plasma subunit:Binds to the C-terminal coiledMutations in TSC2 (tuberous sclerosis 2) lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.