PIAS 3 Polyclonal Antibody, 20ul Peptide Library Promotes integrin alpha-5/beta-1 and fibronectin

Promotes integrin alpha-5/beta-1 and fibronectin (FN) matrix assembly in breast cancer cells

It is a member of the group-II aristaless-related protein family whose members are expressed primarily in the central and/or peripheral nervous system

The protein (branched chain ketoacid dehydrogenase kinase) encoded by BCKDK is found in the mitochondrion

It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells

In comparison to the 2D cell culture

PIAS 3 Polyclonal Antibody, 20ul Peptide Library Promotes integrin alpha-5/beta-1 and fibronectinPIAS3 encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. Protein inhibitor of activated STAT 3 functions as a SUMO (small ubiquitin like modifier) E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity.