Rat Junctional Adhesion Molecule C, JAM3 ELISA Kit, 96T Recombinant Protein NR1H4 and VDR transactivation activity

NR1H4 and VDR transactivation activity

The primary translation product is a 396-residue preprotein which after proteolytic processing is secreted its primary site of synthesis

modulates the dynamic formation of focal adhesions into fibrillar adhesions

It contains an N-terminal caspase recruitment domain (CARD)| a centrally located nucleotide-binding domain (NBD)| and 10 tandem leucine-rich repeats (LRRs) in its C terminus

The stabilization of MYC exerted by PIM1 might explain partly the strong synergism between these two oncogenes in tumorigenesis

Rat Junctional Adhesion Molecule C, JAM3 ELISA Kit, 96T Recombinant Protein NR1H4 and VDR transactivation activityJunctional adhesion protein that mediates heterotypic cell cell interactions with its cognate receptor JAM2 to regulate different cellular processes. Plays a role in homing and mobilization of hematopoietic stem and progenitor cells within the bone marrow. At the surface of bone marrow stromal cells, it contributes to the retention of the hematopoietic stem and progenitor cells expressing JAM3 (By similarity). Plays a central role in leukocytes