CDC37(Phospho-Ser13) Rabbit Polyclonal Antibody, 50ul Immunoassays While the precise function of

While the precise function of the encoded protein is currently unknown| it appears to be involved in mRNA turnover and ribosome assembly

This gene encodes a member of the SIGLEC (sialic acid binding immunoglobulin-like lectin) family of proteins

ZC3H11A has been identified as a protein that is phosphorylated upon DNA damage by ATM or ATR

and murine studies suggest a role in tumor-associated tissue remodeling

It has been shown to bind and activate the ILST/gp130 receoptor

CDC37(Phospho-Ser13) Rabbit Polyclonal Antibody, 50ul Immunoassays While the precise function ofThe protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF 1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.