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Sarcoglycan Alpha Polyclonal Antibody, 20ul Pipette Holder -kb transcript that appears to

SKU: 17029932580

4.6
PLN97.20 PLN127.20

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Sarcoglycan Alpha Polyclonal Antibody, 20ul Pipette Holder -kb transcript that appears toSGCA (sarcoglycan alpha) encodes a component of the dystrophin glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in SGCA result in type 2D autosomal recessive limb girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for

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Description

-kb transcript that appears to be ubiquitously expressed

It may have a role in the development of fragile X mental retardation syndrome

This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5

nuclear phosphoprotein that plays a role in cell cycle progression

Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype

Sarcoglycan Alpha Polyclonal Antibody, 20ul Pipette Holder -kb transcript that appears toSGCA (sarcoglycan alpha) encodes a component of the dystrophin glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in SGCA result in type 2D autosomal recessive limb girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for

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