SYT4 Polyclonal Antibody, 20ul Polyclonal Antibodies This binding tethers the nucleus

This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus

It has been suggested to be involved in several basic biological events such as cell death

this protein regulates Golgi homeostasis and coordinates intra-Golgi retrograde trafficking

Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3)

Knockout studies in mice suggest that PTGES may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses

SYT4 Polyclonal Antibody, 20ul Polyclonal Antibodies This binding tethers the nucleuscofactor: Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,May be involved in Ca(2+) dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.,Belongs to the synaptotagmin family.,Contains 2 C2 domains.,tissue specificity: Expressed in brain. Within brain, expression is highest in hippocampus, with