ZNF420 Polyclonal Antibody, 100ul Peptide Library Nkx2-6 may play a role

Nkx2-6 may play a role in both pharyngeal and cardiac embryonic development

The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance

differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites

This PTP also suppresses JAK kinases

Human macrophages can synthesize a functional chitotriosidase

ZNF420 Polyclonal Antibody, 100ul Peptide Library Nkx2-6 may play a roleZinc finger protein 420 encoded by ZNF420 is a KRAB type zinc finger protein that negatively regulates p53 mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissociates from p53, which activates p53 and initiates apoptosis.