ALK Polyclonal Antibody, 50ul[BT-AP00372] In vitro Assessment It along with PCBP-2 and

It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein

Mutations in this gene are the cause of the autosomal recessive metabolism disorder alkaptonuria

It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner

termed the T-box

Alternatively spliced transcript variants have been found for PTTG1IP

ALK Polyclonal Antibody, 50ul[BT-AP00372] In vitro Assessment It along with PCBP-2 andALK encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. ALK tyrosine kinase receptor comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or