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IGF-IR Polyclonal Antibody, 100ul[BT-AP04397] Reagent Reservoirs which also includes two regulatory

SKU: 17304998311

4.5
PLN123.75 PLN165.75

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IGF-IR Polyclonal Antibody, 100ul[BT-AP04397] Reagent Reservoirs which also includes two regulatoryIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms

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Description

which also includes two regulatory subunits

It can act as either an agonist or antagonist of Wnt/beta-catenin signaling

bronchial and small airway lung epithelial cells (at protein level)

forms laminin-5

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IGF-IR Polyclonal Antibody, 100ul[BT-AP04397] Reagent Reservoirs which also includes two regulatoryIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms

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