IP3R-I(Phospho Ser1764) Polyclonal Antibody, 20ul Peptide Modification represented by this protein

represented by this protein

Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR)

The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport

it is expressed at high levels in peripheral blood leukocytes

Functional analysis showed that this gene product has both ATPase and DNA helicase activities

IP3R-I(Phospho Ser1764) Polyclonal Antibody, 20ul Peptide Modification represented by this proteinThis gene encodes an intracellular receptor for inositol 1,4,5 trisphosphate. Upon stimulation by inositol 1,4,5 trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.