RNF41 Polyclonal Antibody, 20ul Immunology Fractalkine is a member of

Fractalkine is a member of this chemokine family that binds CX3CR1

There are pseudogenes for this gene on chromosomes 2 and 17

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This gene is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE)

Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation

RNF41 Polyclonal Antibody, 20ul Immunology Fractalkine is a member ofThis gene encodes an E3 ubiquitin ligase. The encoded protein plays a role in type 1 cytokine receptor signaling by controlling the balance between JAK2 associated cytokine receptor degradation and ectodomain shedding. Alternative splicing results in multiple transcript variants.