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CD58 Polyclonal Antibody, 50ul[BT-AP02214] Plasmid Preparation one of the ubiquitous factors

SKU: 17573539299

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CD58 Polyclonal Antibody, 50ul[BT-AP02214] Plasmid Preparation one of the ubiquitous factorsATF4 encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax responsive enhancer element in the LTR of HTLV 1. The encoded protein was also isolated and characterized as the cAMP response element binding protein 2 (CREB 2). The protein encoded by this gene belongs to a family of DNA binding proteins that includes the AP 1 family of transcription factors, cAMP response

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Description

one of the ubiquitous factors required for transcription initiation by RNA polymerase II

GO annotations related to this gene include phosphatase binding

The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain

Shorter isoforms of this protein which lack the C-terminal HECT domain are therefore unlikely to bind E2 enzymes

online information:Core 2 beta-1

CD58 Polyclonal Antibody, 50ul[BT-AP02214] Plasmid Preparation one of the ubiquitous factorsATF4 encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax responsive enhancer element in the LTR of HTLV 1. The encoded protein was also isolated and characterized as the cAMP response element binding protein 2 (CREB 2). The protein encoded by this gene belongs to a family of DNA binding proteins that includes the AP 1 family of transcription factors, cAMP response

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