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Moreover, it reveals that possible mechanisms behind this effect might include granulation tissue formation, reepithelialization and deposition of collagen through the ERK1/2 signaling pathway [6] 3

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Immunofluorescence staining The tumor-bearing liver tissues from C57BL/6 mice were frozen section, and then the slices were permeabilized with 0.3% Triton X-100 solution for 15 min at room temperature