ARHGF Polyclonal Antibody, 20ul Adeno-associated Virus Packaging Nitric oxide-sensitive guanylyl cyclase is

Nitric oxide-sensitive guanylyl cyclase is a heterodimeric enzyme consisting of an alpha and a beta subunit

is usually found in tissues containing type II collagen

the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells)

This gene encodes a member of a family of proteins containing several distinct regions

Mutations in this gene are a cause of cardiac septal defects

ARHGF Polyclonal Antibody, 20ul Adeno-associated Virus Packaging Nitric oxide-sensitive guanylyl cyclase isRho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. This gene encodes a protein that functions as a specific guanine nucleotide exchange factor for RhoA. It also interacts with ephrin A4 in vascular smooth muscle cells. Two alternatively spliced transcripts variants that encode the same protein have been found for this gene.