TNPO1 Polyclonal Antibody, 20ul Dialysis PTM:The disulfide bond may lock

PTM:The disulfide bond may lock the enzyme in a closed conformation under oxidized conditions

It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which

Activated upon depolarization

SNX1 encodes a member of the sorting nexin family

Gene Ontology (GO) annotations related to this gene include nucleic acid binding and transcription factor activity

TNPO1 Polyclonal Antibody, 20ul Dialysis PTM:The disulfide bond may lockThis gene encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins.