PAPP1 Polyclonal Antibody, 50ul Rotator The protein encoded by this

The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function

The telomeric and centromeric copies of this gene are nearly identical and encode the same protein

A read-through transcript composed of the upstream SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and ADORA2A (adenosine A2a receptor) gene sequence has been identified

Until 2010

and also to protein kinase C and the phosphatase calcineurin

PAPP1 Polyclonal Antibody, 50ul Rotator The protein encoded by thisThis gene encodes a secreted metalloproteinase which cleaves insulin like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses.