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MARCH1 Polyclonal Antibody, 50ul Multi-Layer Cell Culture System breast and skin tumors

SKU: 1789362289

4.5
USD162.00 USD209.00

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MARCH1 Polyclonal Antibody, 50ul Multi-Layer Cell Culture System breast and skin tumorsMARCH1 (membrane associated ring CH type finger 1) is a member of the MARCH family of membrane bound E3 ubiquitin ligases. MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the

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Description

breast and skin tumors

which are involved in pleiotropic effects of signal transduction

These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family| thereby forming the transcription factor complex AP-1

The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype

which contain N-terminus EF-hand domains and multiple tandem peptide repeats

MARCH1 Polyclonal Antibody, 50ul Multi-Layer Cell Culture System breast and skin tumorsMARCH1 (membrane associated ring CH type finger 1) is a member of the MARCH family of membrane bound E3 ubiquitin ligases. MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the

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