MSH5 Rabbit Polyclonal Antibody, 50ul Immunology The protein encoded by MED27

The protein encoded by MED27 (mediator complex subunit 27) is a subunit of the CRSP (cofactor required for SP1 activation) complex

a central Sec7 domain

A putative pseudogene exists on chromosome 12

which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons

Through its association with RRN3/TIF-IA may be involved in recruitment of Pol I to rDNA promoters

MSH5 Rabbit Polyclonal Antibody, 50ul Immunology The protein encoded by MED27This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing over events during meiosis. This protein plays a role in promoting ionizing radiation induced apoptosis. This protein forms hetero oligomers with another member of this family mutS homolog 4. Polymorphisms in