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NMDA Epsilon 1/2(Phospho Tyr1246/1252) Polyclonal Antibody, 100ul Measuring Instruments and different isoforms can repress

SKU: 17960594737

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NMDA Epsilon 1/2(Phospho Tyr1246/1252) Polyclonal Antibody, 100ul Measuring Instruments and different isoforms can repressThis gene encodes a member of the glutamate gated ion channel protein family. The encoded protein is an N methyl D aspartate (NMDA) receptor subunit. NMDA receptors are both ligand gated and voltage dependent, and are involved in long term potentiation, an activity dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results

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Description

and different isoforms can repress or activate transcription in transfection studies

Roco1 or KIAA1790

This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls

Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A

Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains

NMDA Epsilon 1/2(Phospho Tyr1246/1252) Polyclonal Antibody, 100ul Measuring Instruments and different isoforms can repressThis gene encodes a member of the glutamate gated ion channel protein family. The encoded protein is an N methyl D aspartate (NMDA) receptor subunit. NMDA receptors are both ligand gated and voltage dependent, and are involved in long term potentiation, an activity dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results

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