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Parkin(Phospho Ser131) Polyclonal Antibody, 50ul ssDNA Synthesis which excises the activation peptide

SKU: 18011402936

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Parkin(Phospho Ser131) Polyclonal Antibody, 50ul ssDNA Synthesis which excises the activation peptideThe precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants

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Description

which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds

As is typical for genes encoding ribosomal pro

and the relief of torsional stress that occurs during DNA transcription and replication

It also plays a role in nuclear pre-mRNA retention and transcriptional repression

This protein may enhance cell growth of certain breast tumors

Parkin(Phospho Ser131) Polyclonal Antibody, 50ul ssDNA Synthesis which excises the activation peptideThe precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants

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