Rat Beta-Arrestin-2, ARRB2 ELISA Kit, 96T Cell Function Analysis Variations in GPR126 can affect

Variations in GPR126 can affect a person's stature

Defects in complex I are a common cause of mitochondrial dysfunction

It may be part of a physiologic ligand-receptor complex involved in T-cell activation

Reduces hepatic gluconeogenesis through down-regulation of PEPCK in an isoform Alpha-dependent manner (PubMed: 26711253)

Receptor for the heterotrimeric lymphotoxin containing LTA and LTB

Rat Beta-Arrestin-2, ARRB2 ELISA Kit, 96T Cell Function Analysis Variations in GPR126 can affectFunctions in regulating agonist mediated G protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta arrestins bind to the GPRK phosphorylated receptor and sterically preclude its coupling to the cognate G protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta arrestins target