PRCC Rabbit Polyclonal Antibody, 100ul Dry Bath Mutations in this gene are

Mutations in this gene are associated with Hirschsprung disease

This gene encodes a member of the cadherin superfamily

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell

LGR6 encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily

It is encoded by the single ACHE gene| and the structural diversity in the gene products arises from alternative mRNA splicing| and post-translational associations of catalytic and structural subunits

PRCC Rabbit Polyclonal Antibody, 100ul Dry Bath Mutations in this gene areThis gene encodes a protein that may play a role in pre mRNA splicing. Chromosomal translocations (X; 1)(p11; q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.