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HAO1 Monoclonal Antibody(Mix), 100ul Immune Repertoire Sequencing Following cleavage in the bait

SKU: 18416724622

4.8
PLN141.00 PLN179.00

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HAO1 Monoclonal Antibody(Mix), 100ul Immune Repertoire Sequencing Following cleavage in the baitThis gene is one of three related genes that have 2 hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two carbon substrate. The protein is also active on 2 hydroxy fatty acids. The transcript

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Description

Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase

have been implicated in the progression of inflammatory and autoimmune diseases

Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy| in particular limb-girdle muscular dystrophy| type 2C (LGMD2C)

In Drosophila

The encoded protein interacts with nephrocystin| it is required for normal ciliary development| and it functions in renal tubular development

HAO1 Monoclonal Antibody(Mix), 100ul Immune Repertoire Sequencing Following cleavage in the baitThis gene is one of three related genes that have 2 hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two carbon substrate. The protein is also active on 2 hydroxy fatty acids. The transcript

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