Claudin-4(Phospho Tyr208) Polyclonal Antibody, 100ul Mechanical Pipette The erb-b2 receptor tyrosine kinase

The erb-b2 receptor tyrosine kinase 4 binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation

Has lower activity with Lys-11 and Lys-33-linked ubiquitin chains

an essential cytokine involved in inflammatory response

with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions

A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA

Claudin-4(Phospho Tyr208) Polyclonal Antibody, 100ul Mechanical Pipette The erb-b2 receptor tyrosine kinaseThe protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre and postnatal life. This gene is deleted in