Rsk-1 Polyclonal Antibody, 20ul[BT-AP08034] Centrifugal Filter IGSF8 encodes a member the

IGSF8 encodes a member the EWI subfamily of the immunoglobulin protein superfamily

Alternative splicing of this gene results in multiple transcript variants

whereby some individuals have a functional allele that encodes a full-length protein

48 (DFNB48)

and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol

Rsk-1 Polyclonal Antibody, 20ul[BT-AP08034] Centrifugal Filter IGSF8 encodes a member theRPS6KA1 encodes a member of the RSK (ribosomal S6 kinase) family of serine threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen activated kinase (MAPK) signalling pathway. The activity of Ribosomal protein S6 kinase alpha 1 has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different