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BMP8A Polyclonal Antibody, 100ul Site-directed Mutagenesis An important paralog of this

SKU: 18588941073

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BMP8A Polyclonal Antibody, 100ul Site-directed Mutagenesis An important paralog of thisThis gene encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer. This protein may play a role in development of the reproductive

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Description

An important paralog of this gene is SERINC2

PTM:Phosphorylated in a cell-cycle-dependent manner (from the S phase until mitosis)

which is thought to be related to cytochrom c-mediated cell death pathway

Alternative splicing and the use of alternative promoters results in multiple transcript variants

Overexpression of the encoded protein (cathepsin B) has been associated with esophageal adenocarcinoma and other tumors

BMP8A Polyclonal Antibody, 100ul Site-directed Mutagenesis An important paralog of thisThis gene encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer. This protein may play a role in development of the reproductive

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