PO2F3 Rabbit Polyclonal Antibody, 100ul Organelle Studies Alternate splicing of this gene

Alternate splicing of this gene generates several transcript variants encoding different isoforms

Also exhibits low-fidelity DNA synthesis

cofactor:Binds 1 Fe(3+) ion per subunit

is required for the apoptosis mediated by this protein

Alternatively spliced transcript variants encoding different isoforms have been described for GFRA4

PO2F3 Rabbit Polyclonal Antibody, 100ul Organelle Studies Alternate splicing of this geneThis gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type specific differentiation pathways. The encoded protein is primarily expressed in the epidermis and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein and aberrant promoter methylation of this gene