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FIBA Polyclonal Antibody, 20ul Sample Library Tubes It has structural similarity to

SKU: 1867568917

4.5
SEK97.20 SEK127.20

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FIBA Polyclonal Antibody, 20ul Sample Library Tubes It has structural similarity toThis gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants,

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Description

It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family

GO annotations related to this gene include lipid binding and EH domain binding

suggesting that this gene may have a role in the p53-dependent growth regulatory pathway

disease:Overexpressed in most acute myelogenous leukemia (AML) cases (27 over 29)

This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha)

FIBA Polyclonal Antibody, 20ul Sample Library Tubes It has structural similarity toThis gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants,

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