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Phospho-AR (Y363) Polyclonal Antibody, 20ul Modified Oligos An allelic polymorphism in FCGR2C

SKU: 18709399353

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Phospho-AR (Y363) Polyclonal Antibody, 20ul Modified Oligos An allelic polymorphism in FCGR2CThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. AR

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Description

An allelic polymorphism in FCGR2C results in both coding and non-coding variants

but not in other types of tumors

Among its related pathways are Mineral absorption and Metal ion SLC transporters

The protein encoded by PLN (phospholamban)is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle

but it is thought to be non-coding

Phospho-AR (Y363) Polyclonal Antibody, 20ul Modified Oligos An allelic polymorphism in FCGR2CThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. AR

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