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SOCS-3 Polyclonal Antibody, 20ul Nucleic Acid Extraction This gene is expressed in

SKU: 18909264254

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SOCS-3 Polyclonal Antibody, 20ul Nucleic Acid Extraction This gene is expressed inThis gene encodes a member of the STAT induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN) gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse

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Description

This gene is expressed in tissues with motile cilia or flagella

PTM:Phosphorylation at 'Thr-103' and 'Ser-573' is followed by proteasomal degradation

muscleprovided by has been found to bind Opa protein

The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex

There are alternatively spliced transcript variants described for this gene but the full length nature is not known yet

SOCS-3 Polyclonal Antibody, 20ul Nucleic Acid Extraction This gene is expressed inThis gene encodes a member of the STAT induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN) gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse

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