Mcl-1(Phospho-Ser159/Thr163) Rabbit Polyclonal Antibody, 50ul Immune Cell Preparation This is the rate-limiting step

This is the rate-limiting step in the de novo synthesis of guanine nucleotides

Expressed in Langerhans' cell histiocytosis but not in dermatopathic lymphadenopathy

BLCAP encodes a protein that reduces cell growth by stimulating apoptosis

The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux

and may promote complex formation at DNA repair sites

Mcl-1(Phospho-Ser159/Thr163) Rabbit Polyclonal Antibody, 50ul Immune Cell Preparation This is the rate-limiting stepThis gene encodes an anti apoptotic protein which is a member of the Bcl 2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death inducing.