PURB Polyclonal Antibody, 20ul Serum The encoded protein is thought

The encoded protein is thought to act as a regulator of breast cancer growth and progression by binding to a phosphorylated form of integrin beta4

Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia

Multiple transcript variants encoding different isoforms have been found for KAT8

which contains two zinc finger motifs that are required for hetero- or homo-dimerization

Mutations in this gene have been associated with transient neonatal diabetes mellitus type 1 (TNDM1)

PURB Polyclonal Antibody, 20ul Serum The encoded protein is thoughtThis gene product is a sequence specific, single stranded DNA binding protein. It binds preferentially to the single strand of the purine rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute