SGCG Rabbit Polyclonal Antibody, 20ul Sampling Tubes TNFAIP2 (TNF alpha induced protein

TNFAIP2 (TNF alpha induced protein 2) was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells

Plays a role in the regulation of DNA repair after double-stranded DNA breaks (PubMed: 15314155

thereby physically blocking transcription

Many alternatively spliced transcript variants exist for this gene

and cell cycle progression in response to a variety of extracellular signals

SGCG Rabbit Polyclonal Antibody, 20ul Sampling Tubes TNFAIP2 (TNF alpha induced proteinThis gene encodes gamma sarcoglycan one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin syntrophin alpha and beta dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset