MEP1B Polyclonal Antibody, 50ul Protein Post-translational Modification Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding distinct isoforms have been identified for UBE3B

Mutations in this gene have been associated with adducted thumb-clubfoot syndrome

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids

This protein may also play a role in proper neurotransmission in the dopaminergic and GABAergic systems and mutations in this gene may be associated with certain psychiatric illnesses

Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma

MEP1B Polyclonal Antibody, 50ul Protein Post-translational Modification Alternatively spliced transcript variants encodingMeprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and or beta subunits. Homooligomers of alpha