GCK Polyclonal Antibody, 100ul Metabolic enzymes The A-I and A-IV genes

The A-I and A-IV genes are transcribed from the same strand

include PAK1

Detected at high levels in hipppocampus

Genetic variations of this gene have been associated with Parkinson disease susceptibility

this gene has increased expression

GCK Polyclonal Antibody, 100ul Metabolic enzymes The A-I and A-IV genesHexokinases phosphorylate glucose to produce glucose 6 phosphate, the first step in most glucose metabolism pathways. Alternative splicing of GCK results in three tissue specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. Glucokinase localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose 6 phosphate but remains active