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Phospho-CD32 (Y292) Polyclonal Antibody, 100ul Cell fragmentation and collection Mutations in this gene are

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Phospho-CD32 (Y292) Polyclonal Antibody, 100ul Cell fragmentation and collection Mutations in this gene areThe Fc fragment of IgG receptor IIb encoded by FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.

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Description

Mutations in this gene are associated with susceptibility to obesity in humans

and juvenile macular degeneration

often referred to as L-SIGN)

growth retardation

thereby influencing alternative transcript splicing

Phospho-CD32 (Y292) Polyclonal Antibody, 100ul Cell fragmentation and collection Mutations in this gene areThe Fc fragment of IgG receptor IIb encoded by FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.

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