Huntingtin (Acetyl Lys442) Rabbit Polyclonal Antibody, 20ul Molecular Weight Markers GO annotations related to this

GO annotations related to this gene include DNA-directed RNA polymerase activity and RNA polymerase I transcription factor binding

The protein-coding transcript variant contains gene-specific exons only

This gene encodes the protein for complementation group L

This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis

which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle

Huntingtin (Acetyl Lys442) Rabbit Polyclonal Antibody, 20ul Molecular Weight Markers GO annotations related to thisHuntingtin is a disease gene linked to Huntington's disease a neurodegenerative disorder characterized by loss of striatal neurons. This is thought to be caused by an expanded unstable trinucleotide repeat in the huntingtin gene which translates as a polyglutamine repeat in the protein product. A fairly broad range of trinucleotide repeats (9 35) has been identified in normal controls and repeat numbers in excess of 40 have been described as