Tie-2 Polyclonal Antibody, 50ul[BT-AP09017] Immune Repertoire Sequencing The membrane-bound form has both

The membrane-bound form has both membrane-binding and catalytic domains

The protein is thought to be involved in cell motility

and function of the immune system

The protein encoded by this gene belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins| which regulate molecular chaperone activity by stimulating ATPase activity

Mutations in this gene may be associated with type 2 diabetes in human patients

Tie-2 Polyclonal Antibody, 50ul[BT-AP09017] Immune Repertoire Sequencing The membrane-bound form has bothTEK (TEK receptor tyrosine kinase) encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin like domains, three epidermal growth factor (EGF) like domains and three fibronectin type III repeats. The ligand angiopoietin 1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in TEK