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FAK(Phospho Tyr925) Polyclonal Antibody, 100ul Subcellular Fractions and syndromic craniosynostosis

SKU: 19707260165

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FAK(Phospho Tyr925) Polyclonal Antibody, 100ul Subcellular Fractions and syndromic craniosynostosisThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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Description

and syndromic craniosynostosis

Phosphorylation on Ser-362 by RSK2 in osteoblasts contributes to osteoblast transformation

The encoded protein is a component of a large multimeric complex

ADCY7 encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium

Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P)

FAK(Phospho Tyr925) Polyclonal Antibody, 100ul Subcellular Fractions and syndromic craniosynostosisThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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