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MDM2(Phospho Ser186/S188) Polyclonal Antibody, 100ul Mammalian Expression it has been demonstrated that

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MDM2(Phospho Ser186/S188) Polyclonal Antibody, 100ul Mammalian Expression it has been demonstrated thatThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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Description

it has been demonstrated that the protein actually has protein disulfide isomerase activity

This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins

These optimized lentiviruses deliver efficient

Several alternatively spliced transcript variants have been described for this gene

SCF(FBXO33) directs ubiquitination of YBX1 (By similarity)

MDM2(Phospho Ser186/S188) Polyclonal Antibody, 100ul Mammalian Expression it has been demonstrated thatThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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