IGFBP3 Polyclonal Antibody, 20ul[BT-AP04389] Long RNA Synthesis Three alternatively spliced transcript variants

Three alternatively spliced transcript variants that encode different protein isoforms have been described

may modulate vesicle budding and uncoating within the Golgi apparatus

The encoded protein can bind to the human immunodeficiency virus-1 protein Nef

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which functions as a Cdk-activating kinase (CAK)

IGFBP3 Polyclonal Antibody, 20ul[BT-AP04389] Long RNA Synthesis Three alternatively spliced transcript variantsIGFBP3 is a member of the insulin like growth factor binding protein (IGFBP) family and encodes Insulin like growth factor binding protein 3 with an IGFBP domain and a thyroglobulin type I domain. The protein forms a ternary complex with insulin like growth factor acid labile subunit (IGFALS) and either insulin like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half life of IGFs and altering their interaction