Phospho-AMPKBeta1 (S182) Polyclonal Antibody, 100ul[BT-PHS00011] Molecular Biology Following activation

Following activation

A similar protein in mouse is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signaling pathway transcription factor recombining binding protein J

May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex

Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis|it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics)| abnormalities of brain development| and/or mental retardation of Down syndrome

5 kb transcript has not been characterized

Phospho-AMPKBeta1 (S182) Polyclonal Antibody, 100ul[BT-PHS00011] Molecular Biology Following activationThe protein encoded by PRKAB1 (protein kinase AMP activated non catalytic subunit beta 1) is a regulatory subunit of the AMP activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non catalytic beta and gamma subunits. AMPK is an important energy sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates