Ob Polyclonal Antibody, 50ul[BT-AP12166] Recombinant Ab Production Members of this superfamily are

Members of this superfamily are characterized by a signature 7-transmembrane domain motif

The encoded protein forms a stoichiometric complex with the mTOR kinase| and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase

E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes

|PTM:Phosphorylation by PKB/AKT1 inhibits transcriptional activity and is responsible for cytoplasmic localization

It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family

Ob Polyclonal Antibody, 50ul[BT-AP12166] Recombinant Ab Production Members of this superfamily areThis gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses,