Raf-1(Phospho Tyr341) Polyclonal Antibody, 20ul Inoculating Loops/Needles RUFY1 (RUN and FYVE domain

RUFY1 (RUN and FYVE domain containing 1) encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain

The encoded protein functions as a scaffolding protein and plays roles in ubiquitination and transcription

involved in the maintenance in the progenitor stage by promoting the cell cycle

hypometabolism

and the expression of this gene is a potential marker for exposure to radiation

Raf-1(Phospho Tyr341) Polyclonal Antibody, 20ul Inoculating Loops/Needles RUFY1 (RUN and FYVE domainThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.