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Integrin Beta2 Polyclonal Antibody, 50ul[BT-AP04585] Culture Media NFKB1 appears to have dual

SKU: 20772713115

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Integrin Beta2 Polyclonal Antibody, 50ul[BT-AP04585] Culture Media NFKB1 appears to have dualITGB2 encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell surface proteins that participate in cell adhesion as well as cell surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants.

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Description

NFKB1 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p105 and generation of p50 by a cotranslational processing

it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters

In response to ionizing radiation or oxidative damage| the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids

and uses flavin adenine dinucleotide and folate as cofactors

possibly composed of CATSPER1

Integrin Beta2 Polyclonal Antibody, 50ul[BT-AP04585] Culture Media NFKB1 appears to have dualITGB2 encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell surface proteins that participate in cell adhesion as well as cell surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants.

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