PDE11 Rabbit Polyclonal Antibody, 50ul 3D Culture Mutations in this gene are
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PDE11 Rabbit Polyclonal Antibody, 50ul 3D Culture Mutations in this gene areThe 3' 5' cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3' 5' cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5' monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical
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